{"id":467974,"date":"2026-10-22T10:56:03","date_gmt":"2026-10-22T13:56:03","guid":{"rendered":"https:\/\/mrnews.com.br\/index.php\/2026\/10\/22\/anvisa-aprova-novo-medicamento-para-cancer-de-pulmao-avancado\/"},"modified":"2026-10-22T10:56:03","modified_gmt":"2026-10-22T13:56:03","slug":"anvisa-aprova-novo-medicamento-para-cancer-de-pulmao-avancado","status":"publish","type":"post","link":"https:\/\/mrnews.com.br\/index.php\/2026\/10\/22\/anvisa-aprova-novo-medicamento-para-cancer-de-pulmao-avancado\/","title":{"rendered":"Anvisa aprova novo medicamento para c\u00e2ncer de pulm\u00e3o avan\u00e7ado"},"content":{"rendered":"<p>Por EBC, <\/p>\n<div>\n<p>A Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria (Anvisa) aprovou novo medicamento para o tratamento do\u00a0c\u00e2ncer de pulm\u00e3o. O Emrelis (telisotuzumabe vedotina) \u00e9 indicado para pacientes adultos com c\u00e2ncer de pulm\u00e3o de c\u00e9lulas n\u00e3o pequenas (CPCNP) com as seguintes caracter\u00edsticas: n\u00e3o escamoso, localmente avan\u00e7ado ou metast\u00e1tico, com receptor do fator de crescimento epid\u00e9rmico tipo selvagem, com alta superexpress\u00e3o da prote\u00edna c-Met e que receberam terapia sist\u00eamica previamente.<\/p>\n<p><strong>Em nota, a Anvisa destacou que o medicamento foi desenvolvido para reconhecer e se ligar seletivamente \u00e0 prote\u00edna c-Met presente na superf\u00edcie das c\u00e9lulas tumorais, permitindo a internaliza\u00e7\u00e3o do complexo e a libera\u00e7\u00e3o intracelular da monometilauristatina E, resultando em morte celular direcionada.<\/strong><\/p>\n<p>De acordo com a ag\u00eancia, a aprova\u00e7\u00e3o do Emrelis foi fundamentada sobretudo em resultados de um estudo conduzido em pacientes previamente tratados com CPCNP. O medicamento demonstrou taxa de resposta objetiva de 29,2% na popula\u00e7\u00e3o total avaliada. Entre os pacientes com alta superexpress\u00e3o de c-Met, foi observada taxa de resposta de 34,5%, \u201cassociada a respostas duradouras e benef\u00edcio cl\u00ednico relevante em um cen\u00e1rio terap\u00eautico com op\u00e7\u00f5es limitadas\u201d.<\/p>\n<p><strong>Ainda segundo a Anvisa, o c\u00e2ncer de pulm\u00e3o figura como uma das principais causas de mortalidade pela doen\u00e7a\u00a0no mundo. O CPCNP representa aproximadamente 85% dos casos, sendo que cerca de 70% correspondem ao subtipo n\u00e3o escamoso, alvo da medica\u00e7\u00e3o aprovada.<\/strong><\/p>\n<blockquote>\n<p>\u201cPacientes com doen\u00e7a localmente avan\u00e7ada ou metast\u00e1tica (quando as c\u00e9lulas do tumor se propagam para outras partes do corpo) apresentam progn\u00f3stico desfavor\u00e1vel. Ap\u00f3s a quimioterapia e imunoterapia, h\u00e1 uma limitada disponibilidade de terapias\u201d, refor\u00e7ou a ag\u00eancia.<\/p>\n<\/blockquote>\n<h2>C\u00e2ncer de mama<\/h2>\n<p><strong>A Anvisa tamb\u00e9m aprovou o registro do medicamento Poherdy (pertuzumabe), indicado para o tratamento de c\u00e2ncer de mama metast\u00e1tico e para c\u00e2ncer de mama em est\u00e1gio inicial.<\/strong><\/p>\n<p>No caso da doen\u00e7a metast\u00e1tica, o uso \u00e9 indicado em combina\u00e7\u00e3o com trastuzumabe e docetaxel, voltado para pacientes com c\u00e2ncer de mama HER2-positivo metast\u00e1tico ou localmente recorrente n\u00e3o oper\u00e1vel, que n\u00e3o tenham recebido tratamento pr\u00e9vio com medicamentos anti-HER2 ou quimioterapia.<\/p>\n<p>J\u00e1 para pacientes com c\u00e2ncer de mama inicial, a indica\u00e7\u00e3o \u00e9 o uso combinado com trastuzumabe e quimioterapia, para os seguintes casos:<\/p>\n<p>tratamento neoadjuvante (antes da cirurgia) de pacientes com c\u00e2ncer de mama HER2-positivo localmente avan\u00e7ado, inflamat\u00f3rio ou em est\u00e1gio inicial, com elevado risco de recorr\u00eancia como parte de um esquema terap\u00eautico completo para o c\u00e2ncer de mama inicial.<\/p>\n<p>tratamento adjuvante (ap\u00f3s a cirurgia) de pacientes com c\u00e2ncer de mama HER2-positivo em est\u00e1gio inicial, com elevado risco de recorr\u00eancia.<\/p>\n<p>      <!-- Relacionada --><\/p>\n<p>            <!-- Relacionada -->\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Por EBC, A Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria (Anvisa) aprovou novo medicamento para o tratamento do\u00a0c\u00e2ncer de pulm\u00e3o. O Emrelis (telisotuzumabe vedotina) \u00e9 indicado para pacientes adultos com c\u00e2ncer de pulm\u00e3o de c\u00e9lulas n\u00e3o pequenas (CPCNP) com as seguintes caracter\u00edsticas: n\u00e3o escamoso, localmente avan\u00e7ado ou metast\u00e1tico, com receptor do fator de crescimento epid\u00e9rmico tipo selvagem, &hellip;<\/p>\n","protected":false},"author":39,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[4],"tags":[],"class_list":["post-467974","post","type-post","status-publish","format-standard","hentry","category-servicos"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Anvisa aprova novo medicamento para c\u00e2ncer de pulm\u00e3o avan\u00e7ado<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/agenciabrasil.ebc.com.br\/saude\/noticia\/2026-10\/anvisa-aprova-novo-medicamento-para-cancer-de-pulmao-avancado\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anvisa aprova novo medicamento para c\u00e2ncer de pulm\u00e3o avan\u00e7ado\" \/>\n<meta property=\"og:description\" content=\"Por EBC, A Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria (Anvisa) aprovou novo medicamento para o tratamento do\u00a0c\u00e2ncer de pulm\u00e3o. O Emrelis (telisotuzumabe vedotina) \u00e9 indicado para pacientes adultos com c\u00e2ncer de pulm\u00e3o de c\u00e9lulas n\u00e3o pequenas (CPCNP) com as seguintes caracter\u00edsticas: n\u00e3o escamoso, localmente avan\u00e7ado ou metast\u00e1tico, com receptor do fator de crescimento epid\u00e9rmico tipo selvagem, &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/agenciabrasil.ebc.com.br\/saude\/noticia\/2026-10\/anvisa-aprova-novo-medicamento-para-cancer-de-pulmao-avancado\" \/>\n<meta property=\"og:site_name\" content=\"MRNews\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/eaipahpah\/?locale2=pt_BR\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-22T13:56:03+00:00\" \/>\n<meta name=\"author\" content=\"Fernando Corraa\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@conspirou\" \/>\n<meta name=\"twitter:site\" content=\"@conspirou\" \/>\n<meta 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